OXiGENE is an oncology focused biopharmaceutical company developing vascular disrupting agents (VDAs). VDAs selectively disrupt the abnormal blood vessels that sustain tumors. OXiGENE is dedicated to leveraging its scientific expertise, intellectual property and therapeutic development capabilities to bring life-extending and life-enhancing medicines to patients.
Phase 2 Study
GI-NETs are slow-growing tumors that can spread and produce debilitating symptoms, including episodic flushing, diarrhea, wheezing, and the eventual development of carcinoid heart disease.
After many years of research, we believe that fosbretabulin is poised to become the first commercialized VDA, having shown meaningful clinical activity and tolerability in clinical trials to date.
Vascular Disrupting Agents or “VDAs” block blood flow through established tumor blood vessels, thereby starving tumors of oxygen and essential nutrients, leading to tumor cell death.